Fundc1 phosphorylation antibody
WebFUNDC1 resides on the mitochondrial outer membrane protein and regulates mitochondrial dynamics and hypoxia-induced mitophagy (2-4). … WebAnti-rabbit IgG, HRP-linked Antibody #7074 was used as a secondary antibody. Show More Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc-tagged full-length human BNIP3 protein (hBNIP3-Myc; +), using BNIP3 (D7U1T) Rabbit mAb.
Fundc1 phosphorylation antibody
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WebDec 5, 2024 · FUNDC1 deficiency aggravated DOX-induced cardiac dysfunction, mitochondrial damage and cardiomyocyte PANoptosis. In an effort to discern the mechanistic basis behind FUNDC1-offered regulation... Web72024 Ensembl ENSG00000069509 ENSMUSG00000025040 UniProt Q8IVP5 Q9DB70 RefSeq (mRNA) NM_173794 NM_028058 NM_001313745 NM_001313746 RefSeq …
WebMay 4, 2016 · FUNDC1 is a novel MAM protein and accumulates in the MAM under hypoxic conditions Immunoblots of subcellular fractions from HeLa cells exposed to normoxia. P: post-nuclear supernatant; C: … WebMay 8, 2014 · FUNDC1 Dephosphorylation at Ser-13 Is Associated with the Activation of Mitophagy To understand the regulatory mechanism underlying FUNDC1-mediated mitophagy, we performed mass spectrometric analysis and found that both tyrosine 18 (Tyr-18) and Ser-13 of FUNDC1 were phosphorylated.
WebSeveral mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with … WebFeb 18, 2024 · FUNDC1 was high expression in SRA01/04 cells with H 2 O 2 treatment, whereas hypomethylation of FUNDC1 in cataract lens cells under oxidative stress. The knockdown of FUNDC1 decreased cell apoptosis and autophagy in comparison with the negative control of SRA01/04 cells.
WebMay 9, 2024 · The anti-p-FUNDC1 (ser13) (1:500) and anti-FUNDC1 (1:1000) poly-clonal antibodies were produced by immunizing rabbits with synthesized and purified phosphorylated and nonphosphorylated …
WebMay 10, 2024 · FUNDC1, a highly conserved protein that modulates communication between ER and mitochondria and MAM formation 22, co-localized with both … statistics canada farm cash receiptsWebFUNDC1 Antibody - N-terminal region (ARP53280_P050) Be the first to review this product 25 ug of the indicated Human whole cell extracts was loaded onto a 10-20% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. WB Suggested Anti-FUNDC1 Antibody Titration: 0.2-1 ug/ml Positive Control: Human heart Host: Rabbit … statistics canada eiWebNov 15, 2024 · Furthermore, unc-51 like autophagy activating kinase 1 (ULK1) induces the phosphorylation of FUNDC1 at Ser17, promoting its direct interaction with LC3B and mitophagic activity in response to mitochondrial damage [29]. However, the role of vaspin in mitophagy and atrial fibrosis remains unclear. statistics canada farm censusWebFUNDC1 interacts directly with important autophagy markers such as MAP1LC3B and GABARAP. Phosphorylation at Tyr-18 inactivates FUNDC1 mitophagy activation ability, … statistics canada family violenceWebAntibody Testing Data (1) Application FIGURE 1/1 Phospho-FUNDC1 (Ser17) Antibody (PA5-114576) in WB Western blot analysis of Phospho-FUNDC1 (Ser17) in Human … statistics canada food pricesWebStudies have demonstrated that FUNDC1 plays an essential role in mitophagy under hypoxia or I/R conditions. Li et al. reported that the ULK1 signaling pathway mediates … statistics canada gang violenceWebInterestingly, FUNDC1 seems to play a less important role in starvation-induced mitophagy or CCCP-induced mitophagy, suggesting different mechanisms may be responsible for … statistics canada gen z